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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 2
2009 2
2011 5
2012 1
2013 4
2014 1
2015 1
2016 1
2017 1
2018 5
2019 7
2020 6
2021 3
2022 3
2023 2
2024 0

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40 results

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Page 1
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
Musunuru K, Chadwick AC, Mizoguchi T, Garcia SP, DeNizio JE, Reiss CW, Wang K, Iyer S, Dutta C, Clendaniel V, Amaonye M, Beach A, Berth K, Biswas S, Braun MC, Chen HM, Colace TV, Ganey JD, Gangopadhyay SA, Garrity R, Kasiewicz LN, Lavoie J, Madsen JA, Matsumoto Y, Mazzola AM, Nasrullah YS, Nneji J, Ren H, Sanjeev A, Shay M, Stahley MR, Fan SHY, Tam YK, Gaudelli NM, Ciaramella G, Stolz LE, Malyala P, Cheng CJ, Rajeev KG, Rohde E, Bellinger AM, Kathiresan S. Musunuru K, et al. Among authors: garcia sp. Nature. 2021 May;593(7859):429-434. doi: 10.1038/s41586-021-03534-y. Epub 2021 May 19. Nature. 2021. PMID: 34012082
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F, Orkin SH, Bauer DE. Canver MC, et al. Among authors: garcia sp. Nature. 2015 Nov 12;527(7577):192-7. doi: 10.1038/nature15521. Epub 2015 Sep 16. Nature. 2015. PMID: 26375006 Free PMC article.
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.
Wei Y, Qin Q, Yan C, Hayes MN, Garcia SP, Xi H, Do D, Jin AH, Eng TC, McCarthy KM, Adhikari A, Onozato ML, Spentzos D, Neilsen GP, Iafrate AJ, Wexler LH, Pyle AD, Suvà ML, Dela Cruz F, Pinello L, Langenau DM. Wei Y, et al. Among authors: garcia sp. Nat Cancer. 2022 Aug;3(8):961-975. doi: 10.1038/s43018-022-00414-w. Epub 2022 Aug 18. Nat Cancer. 2022. PMID: 35982179 Free PMC article.
Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia.
Laukkanen S, Veloso A, Yan C, Oksa L, Alpert EJ, Do D, Hyvärinen N, McCarthy K, Adhikari A, Yang Q, Iyer S, Garcia SP, Pello A, Ruokoranta T, Moisio S, Adhikari S, Yoder JA, Gallagher K, Whelton L, Allen JR, Jin AH, Loontiens S, Heinäniemi M, Kelliher M, Heckman CA, Lohi O, Langenau DM. Laukkanen S, et al. Among authors: garcia sp. Blood. 2022 Oct 27;140(17):1891-1906. doi: 10.1182/blood.2021015106. Blood. 2022. PMID: 35544598 Free PMC article.
GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy.
Kasiewicz LN, Biswas S, Beach A, Ren H, Dutta C, Mazzola AM, Rohde E, Chadwick A, Cheng C, Garcia SP, Iyer S, Matsumoto Y, Khera AV, Musunuru K, Kathiresan S, Malyala P, Rajeev KG, Bellinger AM. Kasiewicz LN, et al. Among authors: garcia sp. Nat Commun. 2023 May 15;14(1):2776. doi: 10.1038/s41467-023-37465-1. Nat Commun. 2023. PMID: 37188660 Free PMC article.
Two faces of bivalent domain regulate VEGFA responsiveness and angiogenesis.
Chen J, Liang X, Zhang S, Wang S, Garcia SP, Yan P, Yu H, Li Z, Liu L, Zhang F, Wei W, Le H, Zhang Y, Yuan GC, Chen S, Chen Y, Sun K, Pu WT, Zhang B. Chen J, et al. Among authors: garcia sp. Cell Death Dis. 2020 Jan 30;11(1):75. doi: 10.1038/s41419-020-2228-3. Cell Death Dis. 2020. PMID: 32001672 Free PMC article.
Molecularly distinct models of zebrafish Myc-induced B cell leukemia.
Borga C, Foster CA, Iyer S, Garcia SP, Langenau DM, Frazer JK. Borga C, et al. Among authors: garcia sp. Leukemia. 2019 Feb;33(2):559-562. doi: 10.1038/s41375-018-0328-1. Epub 2018 Dec 20. Leukemia. 2019. PMID: 30573774 Free PMC article. No abstract available.
DNA sequences at a glance.
Pinho AJ, Garcia SP, Pratas D, Ferreira PJ. Pinho AJ, et al. Among authors: garcia sp. PLoS One. 2013 Nov 21;8(11):e79922. doi: 10.1371/journal.pone.0079922. eCollection 2013. PLoS One. 2013. PMID: 24278218 Free PMC article.
40 results